Jatrorrhizine
Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
| Trivial name | Neprotin, Yatrorizine |
| Catalog Number | S3884 |
| Molecular Formula | C20H20NO4 |
| CAS# | 3621-38-3 |
| Inchi | InChI=1S/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1 |
| Inchi Key | MXTLAHSTUOXGQF-UHFFFAOYSA-O |
| SMILES | COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/jatrorrhizine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/jatrorrhizine-chemical-structure-s3884.gif |