Loganin
Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.
| Trivial name | Loganoside |
| Catalog Number | S3835 |
| Molecular Formula | C17H10F6N6O |
| CAS# | 18524-94-2 |
| Inchi | InChI=1S/C17H10F6N6O/c18-16(19,20)11-1-9(2-12(3-11)17(21,22)23)15-27-8-29(28-15)6-13(14(24)30)10-4-25-7-26-5-10/h1-8H,(H2,24,30)/b13-6+ |
| Inchi Key | JFBAVWVBLRIWHM-AWNIVKPZSA-N |
| SMILES | C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=NN(C=N2)C=C(C3=CN=CN=C3)C(=O)N |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/loganin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/loganin-chemical-structure-s3835.gif |