Dehydroevodiamine
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.
Trivial name | DHED |
Catalog Number | S3816 |
Molecular Formula | C19H15N3O |
CAS# | 67909-49-3 |
Inchi | InChI=1S/C19H15N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9H,10-11H2,1H3 |
Inchi Key | VXHNSVKJHXSKKM-UHFFFAOYSA-N |
SMILES | CN1C2=CC=CC=C2C(=O)N3C1=C4C(=C5C=CC=CC5=N4)CC3 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/dehydroevodiamine.html |
Additional Information | https://file.selleck.cn/downloads/struct/dehydroevodiamine-chemical-structure-s3816.gif |