NEM (N-Ethylmaleimide)
NEM (N-Ethylmaleimide) is an organic compound that is derived from maleic acid. It is an irreversible inhibitor of all cysteine peptidases, with alkylation occurring at the active site thiol group. N-Ethylmaleimide (NEM) inactivates endogenous deubiquitinating enzymes (DUBs). N-Ethylmaleimide (NEM) specifically inhibits phosphate transport in mitochondria.
| Trivial name | N/A |
| Catalog Number | S3692 |
| Molecular Formula | C24H42O7P2 |
| CAS# | 128-53-0 |
| Inchi | InChI=1S/C24H42O7P2/c1-11-28-32(26,29-12-2)21(33(27,30-13-3)31-14-4)17-18-15-19(23(5,6)7)22(25)20(16-18)24(8,9)10/h15-17,25H,11-14H2,1-10H3 |
| Inchi Key | YQLJDECYQDRSBI-UHFFFAOYSA-N |
| SMILES | CCOP(=O)(C(=CC1=CC(=C(C(=C1)C(C)(C)C)O)C(C)(C)C)P(=O)(OCC)OCC)OCC |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/n-ethylmaleimide-nem.html |
| Additional Information | https://file.selleck.cn/downloads/struct/n-ethylmaleimide-nem-chemical-structure-s3692.gif |
