NLRP3 Inflammasome Inhibitor I

NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome.

Trivial name N/A
Catalog Number S3680
Molecular Formula C46H47ClN8O9S
CAS# 16673-34-0
Inchi InChI=1S/C46H47ClN8O9S/c1-26-27(2)65-46-39(26)41(29-7-9-30(47)10-8-29)50-35(42-53-52-28(3)54(42)46)25-38(57)49-31-11-13-32(14-12-31)64-24-23-63-22-21-62-20-19-61-18-17-48-34-6-4-5-33-40(34)45(60)55(44 (33)59)36-15-16-37(56)51-43(36)58/h4-14,35-36,48H,15-25H2,1-3H3,(H,49,57)(H,51,56,58)/t35-,36?/m0/s1
Inchi Key RWLOGRLTDKDANT-TYIYNAFKSA-N
SMILES CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)OCCOCCOCCOCCNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8=CC=C(C=C8)Cl)C
Size 25mg
Supplier Page http://www.selleckchem.com/products/nlrp3-Inflammasome-inhibitor-i.html
Additional Information https://file.selleck.cn/downloads/struct/nlrp3-Inflammasome-inhibitor-i-chemical-structure-s3680.gif