PTP Inhibitor II
PTP Inhibitor II (NSC 129010, 4-(Bromoacetyl)anisole) is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with Ki value of 128 μM.
| Trivial name | NSC 129010, 4-(Bromoacetyl)anisole |
| Catalog Number | S3678 |
| Molecular Formula | C46H47ClN8O9S |
| CAS# | 2632-13-5 |
| Inchi | InChI=1S/C46H47ClN8O9S/c1-26-27(2)65-46-39(26)41(29-7-9-30(47)10-8-29)50-35(42-53-52-28(3)54(42)46)25-38(57)49-31-11-13-32(14-12-31)64-24-23-63-22-21-62-20-19-61-18-17-48-34-6-4-5-33-40(34)45(60)55(44 (33)59)36-15-16-37(56)51-43(36)58/h4-14,35-36,48H,15-25H2,1-3H3,(H,49,57)(H,51,56,58)/t35-,36?/m0/s1 |
| Inchi Key | RWLOGRLTDKDANT-TYIYNAFKSA-N |
| SMILES | CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)OCCOCCOCCOCCNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8=CC=C(C=C8)Cl)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/ptp-inhibitor-2.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ptp-inhibitor-2-chemical-structure-s3678.gif |