Dehydrocostus Lactone
Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.
Trivial name | N/A |
Catalog Number | S3615 |
Molecular Formula | C15H18O2 |
CAS# | 477-43-0 |
Inchi | InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h11-14H,1-7H2/t11-,12-,13-,14-/m0/s1 |
Inchi Key | NETSQGRTUNRXEO-XUXIUFHCSA-N |
SMILES | C=C1CCC2C(C3C1CCC3=C)OC(=O)C2=C |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/dehydrocostus-lactone.html |
Additional Information | https://file.selleck.cn/downloads/struct/dehydrocostus-lactone-chemical-structure-s3615.gif |