Sarsasapogenin
Sarsasapogenin (SAR, Parigenin) is a steroidal sapogenin. It can provoke the generation of reactive oxygen species and activate unfolded protein response (UPR) signaling pathways. SAR potently inhibits NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages.
| Trivial name | Parigenin |
| Catalog Number | S3607 |
| Molecular Formula | C27H44O3 |
| CAS# | 126-19-2 |
| Inchi | InChI=1S/C27H44O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28H,5-15H2,1-4H3/t16-,17-,18+,19-,20+,21-,22-,23-,24-,25-,26-,27+/m0/s1 |
| Inchi Key | GMBQZIIUCVWOCD-WWASVFFGSA-N |
| SMILES | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sarsasapogenin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sarsasapogenin-chemical-structure-s3607.gif |