Ensartinib dihydrochloride

Ensartinib dihydrochloride is a potent new-generation ALK inhibitor with high activity against a broad range of known crizotinib-resistant ALK mutations and CNS metastases. It potently inhibits both wild-type ALK and ALK variants (F1174, C1156Y, L1196M, S1206R, T1151, and G1202R mutants) with in vitro IC50s of <4 nM.

Price Not Available 5mg Ensartinib dihydrochloride Supplier Page

Trivial name	X-396 dihydrochloride
Catalog Number	S2934
Molecular Formula	C26H29Cl4FN6O3
CAS#	2137030-98-7
Inchi	InChI=1S/C26H27Cl2FN6O3.2ClH/c1-13-11-35(12-14(2)31-13)26(37)16-4-6-17(7-5-16)32-25(36)20-10-21(24(30)34-33-20)38-15(3)22-18(27)8-9-19(29)23(22)28;;/h4-10,13-15,31H,11-12H2,1-3H3,(H2,30,34)(H,32,36);2 *1H/t13-,14+,15-;;/m1../s1
Inchi Key	IERUINQRGJAECT-ISUJJMBGSA-N
SMILES	CC1CN(CC(N1)C)C(=O)C2=CC=C(C=C2)NC(=O)C3=NN=C(C(=C3)OC(C)C4=C(C=CC(=C4Cl)F)Cl)N.Cl.Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/ensartinib-dihydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/ensartinib-dihydrochloride-chemical-structure-s2934.gif