Aurora Kinase Inhibitor III
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase with an IC50 of 42 nM and has high selectivity for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively).
Trivial name | N/A |
Catalog Number | S2931 |
Molecular Formula | C21H18F3N5O |
CAS# | 879127-16-9 |
Inchi | InChI=1S/C21H18F3N5O/c22-21(23,24)14-3-1-4-15(11-14)26-18-9-10-25-20(29-18)28-17-6-2-5-16(12-17)27-19(30)13-7-8-13/h1-6,9-13H,7-8H2,(H,27,30)(H2,25,26,28,29) |
Inchi Key | RDTDWGQDFJPTPD-UHFFFAOYSA-N |
SMILES | C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)NC4=CC=CC(=C4)C(F)(F)F |
Size | 2mg |
Supplier Page | http://www.selleckchem.com/products/aurora-kinase-inhibitor-iii.html |
Additional Information | https://file.selleck.cn/downloads/struct/aurora-kinase-inhibitor-chemical-structure-s2931.gif |