GW441756
GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2. GW441756 produces a relevant increase of caspase-3 that leads to apoptosis.
| Trivial name | N/A |
| Catalog Number | S2891 |
| Molecular Formula | C14H20N6O5S |
| CAS# | 504433-23-2 |
| SMILES | NC(CCSCC1OC(C(O)C1O)[N]2C=NC3=C2N=CN=C3N)C(O)=O |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/gw-441756.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s2891-gw441756-chemical-structure.png |