Sotrastaurin (AEB071)
Sotrastaurin (AEB071) is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM in a cell-free assay; inactive to PKCζ. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2791 |
| Molecular Formula | C25H22N6O2 |
| CAS# | 425637-18-9 |
| Inchi | InChI=1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,29,32,33) |
| Inchi Key | OAVGBZOFDPFGPJ-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sotrastaurin-aeb071.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Sotrastaurin-AEB071-chemical-structure-s2791.gif |