Nocodazole
Nocodazole is a rapidly-reversible inhibitor of microtubule polymerization, also inhibits Abl, Abl(E255K) and Abl(T315I) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM in cell-free assays, respectively. Nocodazole induces apoptosis.
| Trivial name | R17934, Oncodazole, NSC238159 |
| Catalog Number | S2775 |
| Molecular Formula | C34H29N7O |
| CAS# | 31430-18-9 |
| Inchi | InChI=1S/C34H29N7O/c42-34-39-26-8-4-5-9-31(26)41(34)25-14-16-40(17-15-25)20-22-10-12-24(13-11-22)33-32(23-6-2-1-3-7-23)37-29-18-27-28(36-21-35-27)19-30(29)38-33/h1-13,18-19,21,25H,14-17,20H2,(H,35,36) (H,39,42) |
| Inchi Key | BIWGYFZAEWGBAL-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(N=C6C=C7C(=NC=N7)C=C6N5)C8=CC=CC=C8 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/nocodazole.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Nocodazole-chemical-structure-s2775.gif |