HER2-Inhibitor-1
HER2-Inhibitor-1 is an analog of ARRY-380. ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.
| Trivial name | N/A |
| Catalog Number | S2752 |
| Molecular Formula | C29H27N7O4S |
| CAS# | 937265-83-3 |
| Inchi | InChI=1S/C29H27N7O4S/c1-19-13-21(4-7-26(19)39-22-9-11-36-28(15-22)32-18-34-36)35-29-24-14-20(3-6-25(24)31-17-33-29)27-8-5-23(40-27)16-30-10-12-41(2,37)38/h3-9,11,13-15,17-18,30H,10,12,16H2,1-2H3,(H,31 ,33,35) |
| Inchi Key | QVMNYGOVNWWFKF-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/her2-inhibitor-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Arry-380-chemical-structure-s2752.gif |