HER2-Inhibitor-1
HER2-Inhibitor-1 is an analog of ARRY-380. ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.
| Trivial name | N/A |
| Catalog Number | S2752 |
| Molecular Formula | C19H17F2N3O5 |
| CAS# | 937265-83-3 |
| Inchi | InChI=1S/C19H17F2N3O5/c1-9-8-29-14-7-23-6-12(16(25)17(26)15(23)19(28)24(9)14)18(27)22-5-10-2-3-11(20)4-13(10)21/h2-4,6,9,14,26H,5,7-8H2,1H3,(H,22,27)/t9-,14+/m0/s1 |
| Inchi Key | WCWSTNLSLKSJPK-LKFCYVNXSA-N |
| SMILES | CC1COC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/her2-inhibitor-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Arry-380-chemical-structure-s2752.gif |