PH-797804
PH-797804 is a novel pyridinone inhibitor of p38α with IC50 of 26 nM in a cell-free assay; 4-fold more selective versus p38β and does not inhibit JNK2. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2726 |
| Molecular Formula | C22H19BrF2N2O3 |
| CAS# | 586379-66-0 |
| Inchi | InChI=1S/C22H19BrF2N2O3/c1-12-4-5-14(21(28)26-3)9-18(12)27-13(2)8-19(20(23)22(27)29)30-11-15-6-7-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28) |
| Inchi Key | KCAJXIDMCNPGHZ-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC)N2C(=CC(=C(C2=O)Br)OCC3=C(C=C(C=C3)F)F)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ph-797804.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PH-797804-chemical-structure-s2726.gif |