Zidovudine
Zidovudine (ZDV, Azidothymidine, NSC 602670) is a nucleoside analogue reverse transcriptase inhibitor, used to treat HIV. It could decrease the HDR efficiency and decrease CRISPR-mediated sequence-specific genome knockin events while increaseing knockout efficiency.
| Trivial name | Azidothymidine, NSC 602670 |
| Catalog Number | S2579 |
| Molecular Formula | C27H31FN6OS |
| CAS# | 30516-87-1 |
| Inchi | InChI=1S/C27H31FN6OS/c28-21-3-4-22-20(5-6-29-22)24(21)26-30-23-15-19(17-33-9-7-32(8-10-33)16-18-1-2-18)36-25(23)27(31-26)34-11-13-35-14-12-34/h3-6,15,18,29H,1-2,7-14,16-17H2 |
| Inchi Key | YDNOHCOYQVZOMC-UHFFFAOYSA-N |
| SMILES | C1CC1CN2CCN(CC2)CC3=CC4=C(S3)C(=NC(=N4)C5=C(C=CC6=C5C=CN6)F)N7CCOCC7 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/zidovudine-retrovir.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Zidovudine-retrovir-chemical-structure-s2579.gif |