PF-04457845
PF-04457845 (PF-4457845) is a potent, favorable selective inhibitor of Fatty acid amide hydrolase (FAAH) with IC50 of 7.2 nM and 7.4 nM for hFAAH and rFAAH, respectively. PF-04457845 covalently modifies the active-site serine nucleophile of FAAH with exquisite selectivity relative to other members of the serine hydrolase superfamily.
| Trivial name | PF-4457845 |
| Catalog Number | S2421 |
| Molecular Formula | C18 H13 N7 |
| CAS# | 1020315-31-4 |
| Inchi | InChI=1S/C18H13N7/c19-17-12-10-13(20-22-18(12)23-21-17)15-14-8-4-5-9-25(14)24-16(15)11-6-2-1-3-7-11/h1-10H,(H3,19,21,22,23) |
| Inchi Key | XVECMUKVOMUNLE-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C4=CC5=C(NN=C5N=N4)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pf-04457845.html |
| Additional Information | https://file.selleck.cn/downloads/struct/pf-04457845-chemical-structure-s2421.gif |