PF-3716556
PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+,K+-ATPase, used for the treatment of gastroesophageal reflux disease.
| Trivial name | N/A |
| Catalog Number | S2222 |
| Molecular Formula | C19H24ClN5O3S |
| CAS# | 928774-43-0 |
| Inchi | InChI=1S/C19H24ClN5O3S/c1-10-13-15(21)16(17(27)22-11-3-4-11)29-19(13)23-18(14(10)20)28-9-12(26)25-7-5-24(2)6-8-25/h11H,3-9,21H2,1-2H3,(H,22,27) |
| Inchi Key | TYTGOXSAAQWLPJ-UHFFFAOYSA-N |
| SMILES | CC1=C2C(=C(SC2=NC(=C1Cl)OCC(=O)N3CCN(CC3)C)C(=O)NC4CC4)N |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/PF-3716556.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PF-3716556-chemical-structure-S2222.gif |