PF-3716556
PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+,K+-ATPase, used for the treatment of gastroesophageal reflux disease.
| Trivial name | N/A |
| Catalog Number | S2222 |
| Molecular Formula | C22H26N4O3 |
| CAS# | 928774-43-0 |
| Inchi | InChI=1S/C22H26N4O3/c1-14-5-4-6-19-20(14)17(7-10-29-19)24-18-11-16(22(28)25(3)8-9-27)13-26-12-15(2)23-21(18)26/h4-6,11-13,17,24,27H,7-10H2,1-3H3/t17-/m1/s1 |
| Inchi Key | YBHKBMJREUZHOV-QGZVFWFLSA-N |
| SMILES | CC1=C2C(CCOC2=CC=C1)NC3=CC(=CN4C3=NC(=C4)C)C(=O)N(C)CCO |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/PF-3716556.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PF-3716556-chemical-structure-S2222.gif |