NVP-BHG712
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
| Trivial name | N/A |
| Catalog Number | S2202 |
| Molecular Formula | C27H27N5 |
| CAS# | 940310-85-0 |
| Inchi | InChI=1S/C27H27N5/c1-31-10-12-32(13-11-31)18-19-2-4-20(5-3-19)23-15-24-25(17-30-27(24)29-16-23)21-6-7-26-22(14-21)8-9-28-26/h2-9,14-17,28H,10-13,18H2,1H3,(H,29,30) |
| Inchi Key | QKKIWEILHCXECO-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(NC=C4C5=CC6=C(C=C5)NC=C6)N=C3 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/NVP-BHG712.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NVP-BHG712-chemical-structure-S2202.gif |