Avasimibe
Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.
| Trivial name | CI-1011, PD-148515 |
| Catalog Number | S2187 |
| Molecular Formula | C15H17ClIN3O3 |
| CAS# | 166518-60-1 |
| Inchi | InChI=1S/C15H17ClIN3O3/c1-2-14(22)19-3-5-20(6-4-19)15(23)9-18-12-8-11(17)10(16)7-13(12)21/h2,7-8,18,21H,1,3-6,9H2 |
| Inchi Key | JFIFBWVNHLXJFY-UHFFFAOYSA-N |
| SMILES | C=CC(=O)N1CCN(CC1)C(=O)CNC2=CC(=C(C=C2O)Cl)I |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/Avasimibe(CI-1011).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Avasimibe-CI-1011-chemical-structure-S2187.gif |