BMS-265246
BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay. It is 25-fold more selective for CDK1/2 than CDK4.
| Trivial name | N/A |
| Catalog Number | S2014 |
| Molecular Formula | C25H22F3N5O4S |
| CAS# | 582315-72-8 |
| Inchi | InChI=1S/C24H20F3N5O4S/c1-31-21(8-9-30-31)15-10-20(22(33)29-12-17-6-7-19(13-28-17)37(2,35)36)23(34)32(14-15)18-5-3-4-16(11-18)24(25,26)27/h3-11,13-14H,12H2,1-2H3,(H,29,33) |
| Inchi Key | BSIRHPGCYXLICK-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)C(=O)NCC3=NC=C(C=C3)S(=O)(=O)C)C4=CC=NN4C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/bms-265246.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BMS265246-chemical-structure-s2014.gif |