PF-573228
PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S2013 |
| Molecular Formula | C14H11N3O |
| CAS# | 869288-64-2 |
| Inchi | InChI=1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18) |
| Inchi Key | HWJRIFZDXJKJJN-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/pf-573228.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PF-573228-chemical-structure-s2013.jpg |