KRN 633
KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-α/β and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.
| Trivial name | N/A |
| Catalog Number | S1557 |
| Molecular Formula | C22H27ClN4O5 |
| CAS# | 286370-15-8 |
| SMILES | CC(C)CC(N1CC(=CC1=O)OC2=CC=CC=C2Cl)C(=O)NC3=N[N](CC(O)CO)C=C3 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/KRN-633.html |
| Additional Information | https://file.selleck.cn/downloads/struct/KRN633-chemical-structure-S1557.gif |
