Neflamapimod (VX-745)
Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.
| Trivial name | N/A |
| Catalog Number | S1458 |
| Molecular Formula | C12H8ClNO4S |
| CAS# | 209410-46-8 |
| Inchi | InChI=1S/C12H8ClNO4S/c13-9-6-7-12(11(8-9)14(15)16)19(17,18)10-4-2-1-3-5-10/h1-8H |
| Inchi Key | VZDUQPHKUBZMLW-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)S(=O)(=O)C2=C(C=C(C=C2)Cl)[N+](=O)[O-] |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/VX-745.html |
| Additional Information | https://file.selleck.cn/downloads/struct/VX-745-chemical-structure-S1458.gif |
