Droxinostat
Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
| Trivial name | NS 41080 |
| Catalog Number | S1422 |
| Molecular Formula | C23H18Cl2 F3NO4S |
| CAS# | 99873-43-5 |
| Inchi | InChI=1S/C23H18Cl2F3NO4S/c1-2-34(31,32)16-9-7-14(8-10-16)11-21(30)29-15-12-18(24)22(19(25)13-15)17-5-3-4-6-20(17)33-23(26,27)28/h3-10,12-13H,2,11H2,1H3,(H,29,30) |
| Inchi Key | CEICQMBWAQAIQX-UHFFFAOYSA-N |
| SMILES | CCS(=O)(=O)C1=CC=C(C=C1)CC(=O)NC2=CC(=C(C(=C2)Cl)C3=CC=CC=C3OC(F)(F)F)Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/Droxinostat.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Droxinostat-chemical-structure-S1422.gif |