Ki8751
Ki8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM, >40-fold selective for VEGFR2 than c-Kit, PDGFRα and FGFR-2, little activity to EGFR, HGFR and InsR.
Trivial name | N/A |
Catalog Number | S1363 |
Molecular Formula | C24H18F3N3O4 |
CAS# | 228559-41-9 |
Inchi | InChI=1S/C24H18F3N3O4/c1-32-22-11-15-20(12-23(22)33-2)28-8-7-21(15)34-14-4-6-19(17(27)10-14)30-24(31)29-18-5-3-13(25)9-16(18)26/h3-12H,1-2H3,(H2,29,30,31) |
Inchi Key | LFKQSJNCVRGFCC-UHFFFAOYSA-N |
SMILES | COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/Ki8751.html |
Additional Information | https://file.selleck.cn/downloads/struct/KI8751-chemical-structure-S1363.gif |