Posaconazole
Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.
| Trivial name | SCH 56592, POS |
| Catalog Number | S1257 |
| Molecular Formula | C24H23N7O4 |
| CAS# | 171228-49-2 |
| Inchi | InChI=1S/C24H23N7O4/c1-15-27-14-31(28-15)22-20-19(18(35-2)13-26-22)17(12-25-20)21(32)24(34)30-10-8-29(9-11-30)23(33)16-6-4-3-5-7-16/h3-7,12-14,25H,8-11H2,1-2H3 |
| Inchi Key | QRPZBKAMSFHVRW-UHFFFAOYSA-N |
| SMILES | CC1=NN(C=N1)C2=NC=C(C3=C2NC=C3C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/Posaconazole.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Posaconazole-chemical-structure-S1257.gif |