AG-1024
AG-1024 (Tyrphostin, AGS 200) inhibits IGF-1R autophosphorylation with IC50 of 7 μM, is less potent to IR with IC50 of 57 μM and specifically distinguishes between InsR and IGF-1R (as compared to other tyrphostins).
| Trivial name | Tyrphostin, AGS 200 |
| Catalog Number | S1234 |
| Molecular Formula | C20H21N5O4 |
| CAS# | 65678-07-1 |
| Inchi | InChI=1S/C20H21N5O4/c26-19(15-4-3-5-16(14-15)25(27)28)22-20-21-17-6-1-2-7-18(17)24(20)9-8-23-10-12-29-13-11-23/h1-7,14H,8-13H2,(H,21,22,26) |
| Inchi Key | QTCFYQHZJIIHBS-UHFFFAOYSA-N |
| SMILES | C1COCCN1CCN2C3=CC=CC=C3N=C2NC(=O)C4=CC(=CC=C4)[N+](=O)[O-] |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ag-1024-tyrphostin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AG-1024-chemical-structure-s1234.gif |