Decitabine
Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.
| Trivial name | Deoxycytidine, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716 |
| Catalog Number | S1200 |
| Molecular Formula | C16H19ClN6O |
| CAS# | 2353-33-5 |
| Inchi | InChI=1S/C16H19ClN6O/c1-10(2)23-9-19-13-14(20-12-5-3-4-11(17)8-12)21-16(18-6-7-24)22-15(13)23/h3-5,8-10,24H,6-7H2,1-2H3,(H2,18,20,21,22) |
| Inchi Key | XZEFMZCNXDQXOZ-UHFFFAOYSA-N |
| SMILES | CC(C)N1C=NC2=C(N=C(N=C21)NCCO)NC3=CC(=CC=C3)Cl |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/Decitabine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Decitabine-chemical-structure-S1200.gif |