WZ4002
WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50 of 2 nM/8 nM in BaF3 cell line; does not inhibit ERBB2 phosphorylation (T798I).
| Trivial name | N/A |
| Catalog Number | S1173 |
| Molecular Formula | C17H11C1F3N5O3 |
| CAS# | 1213269-23-8 |
| Inchi | InChI=1S/C17H11ClF3N5O3/c1-25-13(23-24-16(25)28)8-26-3-2-12(17(19,20)21)14(15(26)27)29-11-5-9(7-22)4-10(18)6-11/h2-6H,8H2,1H3,(H,24,28) |
| Inchi Key | ZIAOVIPSKUPPQW-UHFFFAOYSA-N |
| SMILES | CN1C(=NNC1=O)CN2C=CC(=C(C2=O)OC3=CC(=CC(=C3)C#N)Cl)C(F)(F)F |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/WZ4002.html |
| Additional Information | https://file.selleck.cn/downloads/struct/WZ4002-chemical-structure-S1173.gif |