Triciribine (API-2)
Triciribine (API-2) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.
| Trivial name | NSC 154020, VD-0002, vqd-002, TCN |
| Catalog Number | S1117 |
| Molecular Formula | C5H4N4 |
| CAS# | 35943-35-2 |
| Inchi | InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9) |
| Inchi Key | KDCGOANMDULRCW-UHFFFAOYSA-N |
| SMILES | C1=C2C(=NC=N1)N=CN2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/Triciribine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Triciribine-chemical-structure-S1117.gif |