NVP-ADW742
NVP-ADW742 (GSK 552602A) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
| Trivial name | GSK 552602A, ADW742 |
| Catalog Number | S1088 |
| Molecular Formula | C28H31N5O |
| CAS# | 475488-23-4 |
| Inchi | InChI=1S/C28H31N5O/c29-27-26-25(22-9-6-10-24(15-22)34-18-20-7-2-1-3-8-20)17-33(28(26)31-19-30-27)23-13-21(14-23)16-32-11-4-5-12-32/h1-3,6-10,15,17,19,21,23H,4-5,11-14,16,18H2,(H2,29,30,31)/t21-,23- |
| Inchi Key | LSFLAQVDISHMNB-AFARHQOCSA-N |
| SMILES | C1CCN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/NVP-ADW742.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NVP-ADW742-chemical-structure-S1088.gif |