SL-327
SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII;capable of transport through the blood-brain barrier.
Trivial name | N/A |
Catalog Number | S1066 |
Molecular Formula | C16H12F3N3S |
CAS# | 305350-87-2 |
Inchi | InChI=1S/C16H12F3N3S/c17-16(18,19)14-4-2-1-3-12(14)13(9-20)15(22)23-11-7-5-10(21)6-8-11/h1-8H,21-22H2/b15-13+ |
Inchi Key | JLOXTZFYJNCPIS-FYWRMAATSA-N |
SMILES | C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/SL327.html |
Additional Information | https://file.selleck.cn/downloads/struct/SL327-chemical-structure-S1066.gif |