GSK467
GSK467 is a cell penetrant and selective inhibitor of KDM5B (JARID1B/PLU1) with Ki of 10 nM. GSK467 shows apparent 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other JmJ family members.
| Trivial name | N/A |
| Catalog Number | S0269 |
| Molecular Formula | C22H21NO2S |
| CAS# | 1628332-52-4 |
| Inchi | InChI=1S/C22H21NO2S/c23-20(21(24)25)16-26-22(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16,23H2,(H,24,25)/t20-/m0/s1 |
| Inchi Key | DLMYFMLKORXJPO-FQEVSTJZSA-N |
| SMILES | C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)SCC(C(=O)O)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/gsk467.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk467-chemical-structure-s0269.gif |