Picropodophyllin

Picropodophyllin (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT).

Price Not Available 100 mg Picropodophyllin Supplier Page
Catalog Number T6943
Alternative Name(s) AXL1717 , Picropodophyllin (PPP) , Picropodophyllotoxin , PPP
Research Area Apoptosis|||Tyrosine Kinase/Adaptors
Molecular Formula C22H22O8
CAS# 477-47-4
Purity 98.88%
SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12
Size 100 mg
Supplier Page https://www.targetmol.com/compound/Picropodophyllin
Additional Information https://www.targetmol.com/datasheet/T6943