Picropodophyllin
Picropodophyllin (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT).
| Catalog Number | T6943 |
| Alternative Name(s) | AXL1717 , Picropodophyllin (PPP) , Picropodophyllotoxin , PPP |
| Research Area | Apoptosis|||Tyrosine Kinase/Adaptors |
| Molecular Formula | C22H22O8 |
| CAS# | 477-47-4 |
| Purity | 98.88% |
| SMILES | COc1cc(cc(OC)c1OC)[C@H]1[C@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12 |
| Size | 100 mg |
| Supplier Page | https://www.targetmol.com/compound/Picropodophyllin |
| Additional Information | https://www.targetmol.com/datasheet/T6943 |
