JK-P3
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
| Catalog Number | T4425 |
| Research Area | Angiogenesis|||Tyrosine Kinase/Adaptors |
| Molecular Formula | C18H17N3O3 |
| CAS# | 942655-44-9 |
| Purity | 99.50% |
| SMILES | COc1c(cc(cc1)C(=O)Nc1n[nH]c(c1)c1ccccc1)OC |
| Size | 50 mg |
| Supplier Page | https://www.targetmol.com/compound/JK-P3 |
| Additional Information | https://www.targetmol.com/datasheet/T4425 |