Midostaurin
PKC412(Midostaurin; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.
| Catalog Number | T3211 |
| Alternative Name(s) | N-Benzoylstaurosporine , PKC412 , CGP41231 , CGP 41251 |
| Research Area | Others|||Chromatin/Epigenetic|||Cytoskeletal Signaling |
| Molecular Formula | C35H30N4O4 |
| CAS# | 120685-11-2 |
| Purity | 99.56% |
| SMILES | CO[C@@H]1[C@@H](C[C@@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1 |
| Size | 25 mg |
| Supplier Page | https://www.targetmol.com/compound/Midostaurin |
| Additional Information | https://www.targetmol.com/datasheet/T3211 |