URMC-099

URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).

Price Not Available 100 mg URMC-099 Supplier Page
Catalog Number T6057
Research Area Stem Cells|||Metabolism|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||DNA Damage/DNA Repair|||Angiogenesis|||Autophagy|||Chromatin/Epigenetic|||MAPK
Molecular Formula C27H27N5
CAS# 1229582-33-5
SMILES CN1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CC1
Size 100 mg
Supplier Page https://www.targetmol.com/compound/URMC-099
Additional Information https://www.targetmol.com/datasheet/T6057