URMC-099
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
| Catalog Number | T6057 |
| Research Area | Stem Cells|||Metabolism|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||DNA Damage/DNA Repair|||Angiogenesis|||Autophagy|||Chromatin/Epigenetic|||MAPK |
| Molecular Formula | C27H27N5 |
| CAS# | 1229582-33-5 |
| SMILES | CN1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CC1 |
| Size | 100 mg |
| Supplier Page | https://www.targetmol.com/compound/URMC-099 |
| Additional Information | https://www.targetmol.com/datasheet/T6057 |
