ZK 756326
ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6 μM, in mouse). Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
| Catalog Number | T3360 |
| Alternative Name(s) | ZK756326 2HCl |
| Research Area | Immunology/Inflammation|||Microbiology/Virology |
| Molecular Formula | C21H28N2O3·2HCl |
| CAS# | 874911-96-3 |
| Purity | 99.06% |
| SMILES | OCCOCCN1CCN(CC2=CC(OC3=CC=CC=C3)=CC=C2)CC1 |
| Size | 25 mg |
| Supplier Page | https://www.targetmol.com/compound/ZK 756326 |
| Additional Information | https://www.targetmol.com/datasheet/T3360 |