Gandotinib

LY2784544(Gandotinib) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.

Price Not Available 100 mg Gandotinib Supplier Page
Catalog Number T2638
Alternative Name(s) LY2784544
Research Area Stem Cells|||Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling
Molecular Formula C23H25ClFN7O
CAS# 1229236-86-5
Purity 99.86%
SMILES Cc1cc(n[nH]1)Nc1nn2c(c(nc2c(c1)CN1CCOCC1)C)Cc1c(cc(cc1)Cl)F
Size 100 mg
Supplier Page https://www.targetmol.com/compound/Gandotinib
Additional Information https://www.targetmol.com/datasheet/T2638