Gandotinib
LY2784544(Gandotinib) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.
Catalog Number | T2638 |
Alternative Name(s) | LY2784544 |
Research Area | Stem Cells|||Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling |
Molecular Formula | C23H25ClFN7O |
CAS# | 1229236-86-5 |
Purity | 99.86% |
SMILES | Cc1cc(n[nH]1)Nc1nn2c(c(nc2c(c1)CN1CCOCC1)C)Cc1c(cc(cc1)Cl)F |
Size | 100 mg |
Supplier Page | https://www.targetmol.com/compound/Gandotinib |
Additional Information | https://www.targetmol.com/datasheet/T2638 |