PLX7904
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
| Catalog Number | T6949 |
| Alternative Name(s) | PB04 |
| Research Area | MAPK |
| Molecular Formula | C24H22F2N6O3S |
| CAS# | 1393465-84-3 |
| SMILES | CCN(C)S(=O)(=O)NC1=CC=C(F)C(C(=O)C2=CNC3=NC=C(C=C23)C2=CN=C(N=C2)C2CC2)=C1F |
| Size | 2 mg |
| Supplier Page | https://www.targetmol.com/compound/PLX7904 |
| Additional Information | https://www.targetmol.com/datasheet/T6949 |