Shikonin
Shikonin is an TMEM16A chloride channel inhibitor (IC50: 6.5 μM). Shikonin is also a selective PKM2 inhibitor and can also suppress activation of the NF-κB pathway and inhibit TNF-α. Shikonin decreases exosome secretion through the inhibition of glycolysis
Catalog Number | T1125 |
Alternative Name(s) | NSC 252844 , Isoarnebin 4 , (+)-Shikonin , Alkanna Red , C.I. 75535 , Anchusa acid |
Research Area | Membrane transporter/Ion channel|||NF-Κb|||Proteases/Proteasome|||Metabolism|||Apoptosis|||Microbiology/Virology |
Molecular Formula | C16H16O5 |
CAS# | 517-89-5 |
Purity | 98.54% |
SMILES | C\C(C)=C\C[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O |
Size | 200 mg |
Supplier Page | https://www.targetmol.com/compound/Shikonin |
Additional Information | https://www.targetmol.com/datasheet/T1125 |