Aripiprazole is a multiple-target agent used to treat schizophrenia and bipolar disorder, working as both a silent antagonist and a high-efficacy partial agonist of D2 receptor, as well as works as a partial agonist of 5-HT1A/5-HT2A, 5-HT2 receptor,a potent inverse agonist of 5-HT2B receptor, a functional antagonist of 5-HT7 receptor.