Doramapimod
Doramapimod is a highly selective p38α MAPK inhibitor with Kd of 0.1 nM, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2, ZAP-70, EGFR, HER2, PKA, PKC, PKCα/β/γ.
| Trivial name | BIRB 796 |
| Catalog Number | CSN10856 |
| Alternative Name(s) | BIRB 796 |
| Research Area | Immunology/Inflammation |
| Molecular Formula | C31H37N5O3 |
| CAS# | 285983-48-4 |
| Purity | ≥99% |
| SMILES | O=C(NC1=C2C=CC=CC2=C(OCCN3CCOCC3)C=C1)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5 |
| Size | 50mg |
| Supplier Page | https://www.csnpharm.com/products/doramapimod.html |