Tanshinone I
Tanshinone I, an active principle isolated from the roots of Salvia miltiorrhiza (Danshen), is an inhibitor of type IIA human recombinant sPLA2 and rabbit recombinant cPLA2 with IC50s of 11 μM and 82 μM, respectively, is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells. Tanshinone I showed inhibitory effect on PL(pro) with IC50 value of 8.8μM and less inhibitory effect on 3CLpro with IC50 value of 38.7μM.
Trivial name | Tanshinone-I |
Catalog Number | CSN12435 |
Alternative Name(s) | Tanshinone-I |
Research Area | Cancer|Cardiovascular Disease|Metabolic Disease|Infection |
Molecular Formula | C18H12O3 |
CAS# | 568-73-0 |
Purity | ≥98% |
SMILES | O=C(C1=C2C=CC3=C1C=CC=C3C)C(C4=C2OC=C4C)=O |
Size | 5mg |
Supplier Page | https://www.csnpharm.com/products/tanshinone-i.html |