Cyclopamine
Cyclopamine is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 cells.
| Trivial name | 11-Deoxojervine |
| Catalog Number | CSN10720 |
| Alternative Name(s) | 11-Deoxojervine |
| Research Area | Cancer |
| Molecular Formula | C27H41NO2 |
| CAS# | 4449-51-8 |
| Purity | ≥99% |
| SMILES | O[C@@H]1CC2=CC[C@]3([H])[C@]([C@@]2(C)CC1)([H])CC4=C(C)[C@@]5(O[C@@]6([H])[C@@]([C@H]5C)([H])NC[C@@H](C)C6)CC[C@@]34[H] |
| Size | 10mg |
| Supplier Page | https://www.csnpharm.com/products/cyclopamine.html |