(-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM. IC50 & Target: EC50: 237 μM (GABA receptor)[1] In Vitro: (-)-Borneol is an enantiomer of (+)-Borneol. (+)-Borneol is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM. At high concentrations (>1.5 mM), (-)-Borneol directly activates GABAA receptors producing 84% of the maximal GABA response indicative of a weak partial agonist action. (-)-Borneol produces dose-dependent positive modulation of the Cl conductance generated by extremely low dose GABA at α1β2γ2L GABAA receptors[1].

Price Not Available 10mM/1mL (-)-Borneol Supplier Page
Trivial name (-)-Borneol
Catalog Number HY-N1368B
Alternative Name(s) L-Borneol
Research Area Neurological Disease
CAS# 464-45-9
Purity ≥98%
Size 10mM/1mL
Supplier Page https://www.medchemexpress.com/_-_-Borneol.html