2-Methoxyestradiol (2-MeOE2)

2-Methoxyestradiol (2-MeOE2, NSC 659853, 2-ME2) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines.

Trivial name NSC 659853, 2-ME2
Catalog Number S1233
Molecular Formula C19H26O3
CAS# 362-07-2
Inchi InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1
Inchi Key CQOQDQWUFQDJMK-SSTWWWIQSA-N
SMILES CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O
Size 1g
Supplier Page http://www.selleckchem.com/products/2-Methoxyestradiol(2ME2).html
Additional Information https://file.selleck.cn/downloads/struct/2-Methoxyestradiol-chemical-structure-S1233.gif