(–)-DHMEQ is a potent NF-κB inhibitor. IC50 & Target: NF-κB[1] In Vitro: (–)-DHMEQ binds to cysteine 38 of RelA and cysteine 144 of RelB. (−)-DHMEQ at concentrations greater than 25 µM inhibits the LTβ-induced nuclear translocation of FLAG-RelB WT, whereas the inhibitory effect of (–)-DHMEQ on the nuclear translocation of FLAG-RelB (C144S) became weaker at the same concentrations[1].

Price Not Available 25mg (-)-DHMEQ Supplier Page
Trivial name (-)-DHMEQ
Catalog Number HY-14645
Alternative Name(s) Dehydroxymethylepoxyquinomicin
Research Area Cancer
CAS# 287194-40-5
Purity ≥98%
Size 25mg
Supplier Page https://www.medchemexpress.com/_-_-DHMEQ.html