MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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Macrocarpal C | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation[1].

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Macrocarpal I | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC50 value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni[1].

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Macrophage Related Compound Library | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Macrophages are effector cells of the innate immune system, engulfing bacteria and secreting pro-inflammatory and antibacterial mediators. They are an important component of the first line defense against pathogens and tumor cells. In addition, macrophages play an important role in eliminating damaged cells through programmed cell death. Like all immune cells, macrophages originate from pluripotent […]

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Maculatin 1.1 TFA | MedChemExpress (MCE) 500 μg  | ≥98.00%

MedChem Express

Maculatin 1.1 TFA is an antimicrobial peptide with an MIC against Staphylococcus aureus of 7 μM. Maculatin 1.1 TFA can perforate the bacterial membrane of Staphylococcus aureus, causing bacterial death[1].

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Maculatin 1.1 TFA | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Maculatin 1.1 TFA is an antimicrobial peptide with an MIC against Staphylococcus aureus of 7 μM. Maculatin 1.1 TFA can perforate the bacterial membrane of Staphylococcus aureus, causing bacterial death[1].

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Maculosidine | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Maculosidine is a furoquinoline alkaloid that can be isolated from Balfourodendron riedelianum. Maculosidine inhibits ATP synthesis, basal, phosphorylating and uncoupled electron transport in plants. Maculosidine inhibits Hill reaction on spinach chloroplasts[1].

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Madecassic acid (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Madecassic acid (Standard) is the analytical standard of Madecassic acid. This product is intended for research and analytical applications. Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells[1].

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Maduramicin | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Maduramicin (Maduramycin) is isolated from the actinomycete Actinomadura rubra. Maduramicin is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection[1]. Maduramicin induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways[2].

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Maftivimab | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Maftivimab (REGN3470-3471-3479), the inhibitor of Filovirus, is an Food and agent Administration (FDA)-approved agent. Maftivimab, also named as Atoltivimab, Odesivimab (Inmazeb), can be used for research of Zaire ebolavirus infection[1].

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MAGL-IN-10 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

MAGL-IN-10 is areversible monoacylglycerol lipase (MAGL) inhibitor with very good ADME properties and low in vivo toxicity.MAGL-IN-10 can be used for the research ofcancer, neurological disorders and inflammatory pathologies[1].

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MAGL-IN-12 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

SAR127303 is an orally active, selective, competitive monoacylglycerol lipase (MAGL) covalent inhibitor with IC50s of 3.8 nM and 29 nM for mouse and human MAGL, respectively. SAR127303 potently elevates hippocampal levels of 2-AG in mice. SAR127303 decreased long term potentiation (LTP) of CA1 synaptic transmission and acetylcholine release in the hippocampus. SAR127303 produces antinociceptive effects […]

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MAGL-IN-13 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

MAGL-IN-13 (compound (3R, 4S) – 5v) is a selective, irreversible inhibitor for MAGL,with IC50 values of 0.026, 0.021 and 0.24 nM for mMAGL, hMAGL and rMAGL, respectively. MAGL-IN-13 can penetrant blood brain barrier. [1].

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Magmas-IN-1 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Magmas-IN-1 (compound 9) is a small molecule Magmas inhibitor (SMMI). Magmas is mitochondria associated,granulocyte-macrophage colony stimulating factor signaling molecule,as well as a GM-CSF inducible gene in myeloid cells. Magmas-IN-1 inhibits Magmas and modulates mitochondrial function. Magmas-IN-1 also inhibits proliferation in yeast at 4 μM[1].

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Magnesium acetate tetrahydrate | MedChemExpress (MCE) 1 g  | ≥99.00%

MedChem Express

Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt. As a salt form of Magnesium, Magnesium acetate tetrahydrate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium acetate tetrahydrate can be used as an electrolyte supplementation or a reagent in molecular biology experiments[1].

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Magnesium stearate | MedChemExpress (MCE) 500 g  | ≥98.00%

MedChem Express

Magnesium stearate is a commonly used pharmaceutical lubricant. But Magnesium stearate leads to an adverse effect on bonding between particles. Magnesium stearate can be used as an excipient, such as lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to […]

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Magnesium stearate | MedChemExpress (MCE) 1 k g  | ≥98.00%

MedChem Express

Magnesium stearate is a commonly used pharmaceutical lubricant. But Magnesium stearate leads to an adverse effect on bonding between particles. Magnesium stearate can be used as an excipient, such as lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to […]

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Magnoloside B | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Magnoloside B is an α-glucosidase inhibitor (IC50=0.69 mM), which can be obtained from Magnolia officinalis stem bark. Magnoloside B shows moderate inhibitory activity against MGC-803 and HepG2 cells. Magnoloside B has the potential to study cancer and diabetes[1].

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Majoranaquinone | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Majoranaquinone exhibits a high antibacterial effect against 4 Staphylococcus, 1 Moraxella, and 1 Enterococcus strains. Majoranaquinone shows substantial efflux pump inhibitory activity in Escherichia coliATCC 25922 strain. Majoranaquinone is found to be an effective biofilm formation inhibitor on E.coli, ATCC 25922 and E. coli K-12 AG100 bacteria[1].

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MAK683-CH2CH2COOH hydrochloride | MedChemExpress (MCE) 5 mg  | ≥98.00%

MedChem Express

MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1].

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MAK683-CH2CH2COOH hydrochloride | MedChemExpress (MCE) 10 mg  | ≥98.00%

MedChem Express

MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1].

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MAK683-CH2CH2COOH hydrochloride | MedChemExpress (MCE) 25 mg  | ≥98.00%

MedChem Express

MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1].

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MAK683-CH2CH2COOH hydrochloride | MedChemExpress (MCE) 50 mg  | ≥98.00%

MedChem Express

MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1].

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MAK683-CH2CH2COOH hydrochloride | MedChemExpress (MCE) 100 mg  | ≥98.00%

MedChem Express

MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1].

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